Opioid withdrawal symptoms can block your path to recovery.

LUCEMYRA® is the only FDA-approved, non-opioid medicine proven to help with symptoms of opioid withdrawal.

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LUCEMYRA can help relieve withdrawal symptoms

Significantly improves the percentage of patients who successfully complete withdrawal treatment

Demonstrated safety profile in studies

Provides the biggest improvement in symptom relief when symptoms were often most severe


Patient Resources

See a collection of interactive and downloadable content, and links to external organizations


Eligible patients will pay $0* for LUCEMYRA. *See Terms and Conditions for details

2020 ASAM National Practice Guideline: Recommendations for Treating Opioid Withdrawal

The American Society of Addiction Medicine (ASAM) recognizes two main strategies for managing opioid withdrawal: gradually tapering the dose of the current opioid(s), or using a non-opioid medication, like LUCEMYRA (lofexidine).
Regarding the use of alpha-2 adrenergic agonists, the Guideline states:

“Lofexidine should therefore be the preferred choice for withdrawal management in an outpatient setting, where monitoring of blood pressure and management of hypotension is more difficult.”

-American Society of Addiction Medicine, 2020

Get Started with LUCEMYRA

Find a healthcare provider who can discuss treatment for opioid withdrawal symptoms with LUCEMYRA.

Photos within this website are actor portrayals.