Frequently Asked Questions

LUCEMYRA is a non-opioid prescription medicine used in adults to provide relief from the symptoms of opioid withdrawal that may happen when you stop taking an opioid suddenly.
Stopping opioid use can result in severe symptoms that are known as Opioid Withdrawal Syndrome (OWS), including:
  • Aches and pains
  • Stomach cramps
  • Feeling sick (nausea, vomiting, diarrhea)
  • Muscle spasms/twitching
  • Insomnia/problems sleeping
  • Feelings of coldness/chills
  • Muscular tension
  • Heart pounding
  • Runny eyes
  • Yawning
  • Sweating
Symptoms of opioid withdrawal occur in people who have first developed an opioid tolerance. Tolerance happens when the body’s response to opioids changes.
Opioid Use Disorder, also called opioid addiction, is the chronic use of opioids that causes clinically significant distress or impairment. LUCEMYRA should be used as a part of a complete treatment program for OUD. This program continues after LUCEMYRA treatment is completed and may also include maintenance medications combined with behavioral counseling.
The severity and length of withdrawal symptoms depend on the type of opioid and how long it is active in your system. Symptoms may vary person to person.
  • For shorter-acting opioids, such as Percocet®, OxyContin®, or Vicodin®, withdrawal symptoms peak within 2 to 3 days and last for 7 to 10 days.
  • For longer-acting opioids, such as methadone, buprenorphine, or fentanyl, withdrawal symptoms peak at 3 to 4 days, but may last for 14 days or more.
LUCEMYRA helps correct a chemical imbalance that causes withdrawal symptoms. Your healthcare provider can tell you about how opioids can affect the chemical imbalance in your brain and how LUCEMYRA can help.
LUCEMYRA may mitigate, but not completely prevent, the symptoms associated with opioid withdrawal.
Be sure to tell your healthcare provider if you take benzodiazepines, barbiturates, tranquilizers, or sleeping pills. Taking LUCEMYRA with these medications can cause serious side effects.
No, LUCEMYRA is not an opioid. It is not a narcotic. It is not addictive.
For more information on dosing, please visit our dosing guide. Make sure you follow the exact dosing instructions provided by your healthcare provider.
  • Low blood pressure or symptoms of low blood pressure, such as lightheadedness
  • Slow heart rate
  • Dizziness
  • Sleepiness
  • Dry mouth

To report SUSPECTED ADVERSE REACTIONS or product complaints, contact US WorldMeds at 1-833-LUCEMYRA. You may also report SUSPECTED ADVERSE REACTIONS to the FDA at 1-800-FDA-1088 or



Learn more about how LUCEMYRA can help relieve withdrawal symptoms you may experience when you suddenly stop taking opioids.


Use our interactive map to find a healthcare provider who can discuss treatment for opioid withdrawal symptoms with LUCEMYRA.


Learn more about our interactive, downloadable, and other resources available to you.