• Each day, patients used a questionnaire to describe how they felt during the previous day of opioid withdrawal, which included rating the following symptoms2,3:
  • Aches and pains
  • Stomach cramps
  • Feeling sick (nausea, vomiting, diarrhea)
  • Muscle spasms/twitching
  • Insomnia/problems sleeping
  • Feelings of coldness/chills
  • Muscular tension
  • Heart pounding
  • Runny eyes
  • Yawning

Patients started to feel some symptom relief

Patients experienced an improvement in symptom relief

Patients continued to experience an improvement in symptom relief, as withdrawal symptoms continued to decrease

LUCEMYRA continued to be effective through Day 7 of treatment.1,4

LUCEMYRA improved the percentage of patients who successfully completed withdrawal treatment1,4

LUCEMYRA is not a treatment for Opioid Use Disorder (OUD), which is also called opioid addiction. If you have been diagnosed with OUD, your healthcare provider may prescribe LUCEMYRA as part of a complete treatment program for your OUD. This program continues after LUCEMYRA treatment is completed and may also include maintenance medications combined with behavioral counseling.


  1. LUCEMYRA® (lofexidine) [Prescribing Information]. Louisville, KY: US WorldMeds, LLC; 2018.
  2. Vernon MK, Reinders S, Mannix S, et al. Psychometric evaluation of the 10-item Short Opiate Withdrawal Scale-Gossop (SOWS-Gossop) in patients undergoing opioid detoxification. Addict Behav. 2016;60:109-116.
  3. Gossop M. The development of a Short Opiate Withdrawal Scale (SOWS). Addict Behav. 1990;15(5):487-490.
  4. Data on file. Louisville, KY: US WorldMeds; 2017.